Mohamed T. M. Nemr

New fused pyrimidine derivatives with anticancer activity: Synthesis, topoisomerase II inhibition, apoptotic inducing activity and molecular modeling study

Mohamed T. M. Nemr, Asmaa M. AboulMagd · Bioorganic Chemistry · 2020 · 76 citations

Medicinal Chemistry, Molecular Modeling Study, Bioorganic Chemistry +11

Design, synthesis and mechanistic study of new benzenesulfonamide derivatives as anticancer and antimicrobial agents <i>via</i> carbonic anhydrase IX inhibition

Mohamed T. M. Nemr, Asmaa M. AboulMagd, Hossam M. Hassan et al. · RSC Advances · 2021 · 75 citations · Full text

Design, synthesis and biological evaluation of new 2-aminothiazole scaffolds as phosphodiesterase type 5 regulators and COX-1/COX-2 inhibitors

Abdel Haleem M. Hussein, Ahmed A. Khames, Abu‐Bakr A. A. M. El‐Adasy et al. · RSC Advances · 2020 · 48 citations · Full text

Design, synthesis and antiproliferative evaluation of new tricyclic fused thiazolopyrimidines targeting topoisomerase II: Molecular docking and apoptosis inducing activity

Mohamed T. M. Nemr, Amr Sonousi, Adel A. Marzouk · Bioorganic Chemistry · 2020 · 46 citations

Molecular Docking, Combinatorial Chemistry, Medicinal Chemistry +10

Discovery of novel pyrazole based Urea/Thiourea derivatives as multiple targeting VEGFR-2, EGFRWT, EGFRT790M tyrosine kinases and COX-2 Inhibitors, with anti-cancer and anti-inflammatory activities

Wael A. A. Fadaly, Mohamed T. M. Nemr, Nesma M. Kahk · Bioorganic Chemistry · 2024 · 44 citations

Medicinal Chemistry, Urology, Novel Pyrazole +11