Wael A. A. Fadaly

Design, synthesis, modeling studies and biological evaluation of thiazolidine derivatives containing pyrazole core as potential anti-diabetic PPAR-γ agonists and anti-inflammatory COX-2 selective inhibitors

Khaled R.A. Abdellatif, Wael A. A. Fadaly, Gehan M. Kamel et al. · Bioorganic Chemistry · 2018 · 100 citations

Derivatives, Biochemistry, Medicine +8

New 1,2,4-triazole/pyrazole hybrids linked to oxime moiety as nitric oxide donor celecoxib analogs: Synthesis, cyclooxygenase inhibition anti-inflammatory, ulcerogenicity, anti-proliferative activities, apoptosis, molecular modeling and nitric oxide release studies

Wael A. A. Fadaly, Yaseen A. M. M. Elshaier, Emad H. M. Hassanein et al. · Bioorganic Chemistry · 2020 · 85 citations

Medicinal Chemistry, Biochemistry, Donor Celecoxib Analogs +11

Non-acidic 1,3,4-trisubstituted-pyrazole derivatives as lonazolac analogs with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile

Khaled R.A. Abdellatif, Wael A. A. Fadaly, Yaseen A. M. M. Elshaier et al. · Bioorganic Chemistry · 2018 · 62 citations

Gastric Safety Profile, Medicinal Chemistry, Promising Cox-2 Selectivity +9

Thiohydantoin derivatives incorporating a pyrazole core: Design, synthesis and biological evaluation as dual inhibitors of topoisomerase-I and cycloxygenase-2 with anti-cancer and anti-inflammatory activities

Khaled R.A. Abdellatif, Wael A. A. Fadaly, Yaser A. Mostafa et al. · Bioorganic Chemistry · 2019 · 56 citations

Medicinal Chemistry, Biochemistry, Dual Inhibitors +12

Synthesis, cyclooxygenase inhibition, anti-inflammatory evaluation and ulcerogenic liability of new 1,3,5-triarylpyrazoline and 1,5-diarylpyrazole derivatives as selective COX-2 inhibitors

Khaled R.A. Abdellatif, Eman K. A. Abdelall, Wael A. A. Fadaly et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 52 citations · Full text

Medicinal Chemistry, Cyclooxygenase Inhibition, Anti-inflammatory +12