Kwang‐Su Park

Discovery of a first-in-class EZH2 selective degrader

Anqi Ma, Kwang‐Su Park, Jieli Wei et al. · Nature Chemical Biology · 2019 · 227 citations · Full text

Life Sciences, Genetics, Molecular Biology +4

EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis

Jun Wang, Xufen Yu, Weida Gong et al. · Nature Cell Biology · 2022 · 183 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models

Xufen Yu, Dongxu Li, Jithesh Kottur et al. · Science Translational Medicine · 2021 · 157 citations · Full text

Medicine, Molecular Biology, Oncology +8

Harnessing the E3 Ligase KEAP1 for Targeted Protein Degradation

Jieli Wei, Fanye Meng, Kwang‐Su Park et al. · Journal of the American Chemical Society · 2021 · 140 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

In vitro solubility, stability and permeability of novel quercetin–amino acid conjugates

Mi Kyoung Kim, Kwang‐Su Park, Woon‐Seok Yeo et al. · Bioorganic & Medicinal Chemistry · 2008 · 130 citations

Pharmacy, Medicinal Chemistry, Pharmaceutics +12