Marika Manolopoulou

Structure of Substrate-free Human Insulin-degrading Enzyme (IDE) and Biophysical Analysis of ATP-induced Conformational Switch of IDE

Hookang Im, Marika Manolopoulou, E. Malito et al. · Journal of Biological Chemistry · 2007 · 117 citations · Full text

Protein Assembly, Closed Conformation, Molecular Biology +16

Molecular Basis of Catalytic Chamber-assisted Unfolding and Cleavage of Human Insulin by Human Insulin-degrading Enzyme

Marika Manolopoulou, Qing Guo, E. Malito et al. · Journal of Biological Chemistry · 2009 · 108 citations · Full text

Designed Inhibitors of Insulin-Degrading Enzyme Regulate the Catabolism and Activity of Insulin

Malcolm A. Leissring, E. Malito, Sabrine Hédouin et al. · PLoS ONE · 2010 · 106 citations · Full text

Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-α, and Amylin by Human Insulin-Degrading Enzyme

Qing Guo, Marika Manolopoulou, Yao Bian et al. · Journal of Molecular Biology · 2009 · 84 citations

Human Insulin-degrading Enzyme, Protein Expression, Cellular Enzymology +8

Molecular Bases for the Recognition of Short Peptide Substrates and Cysteine-Directed Modifications of Human Insulin-Degrading Enzyme

E. Malito, Luis A. Ralat, Marika Manolopoulou et al. · Biochemistry · 2008 · 82 citations · Full text