Thomas Colatsky

Long QT Syndrome Patients With Mutations of the <i>SCN5A</i> and <i>HERG</i> Genes Have Differential Responses to Na ⁺ Channel Blockade and to Increases in Heart Rate

Peter J. Schwartz, Silvia G. Priori, Emanuela H. Locati et al. · Circulation · 1995 · 816 citations

Medicine, Cardiology, Pharmacology +16

The Comprehensive in Vitro Proarrhythmia Assay (CiPA) initiative — Update on progress

Thomas Colatsky, Bernard Fermini, Gary A. Gintant et al. · Journal of Pharmacological and Toxicological Methods · 2016 · 463 citations · Full text

Medicine, Cardiology, Pharmacology +17

Uniform assessment and ranking of opioid Mu receptor binding constants for selected opioid drugs

Donna A. Volpe, R. Daniel Mellon, Aspandiar G. Katki et al. · Regulatory Toxicology and Pharmacology · 2011 · 440 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Mechanisms of action of lidocaine and quinidine on action potential duration in rabbit cardiac Purkinje fibers. An effect on steady state sodium currents?

Thomas Colatsky · Circulation Research · 1982 · 211 citations · Full text

Medicine, Pharmacology, Physiology +17

Improving the In Silico Assessment of Proarrhythmia Risk by Combining hERG (Human Ether-à-go-go-Related Gene) Channel–Drug Binding Kinetics and Multichannel Pharmacology

Zhihua Li, Sara Dutta, Jiansong Sheng et al. · Circulation Arrhythmia and Electrophysiology · 2017 · 205 citations · Full text

Medicine, Cardiology, Pharmacology +17