Zhihua Li

Improving the In Silico Assessment of Proarrhythmia Risk by Combining hERG (Human Ether-à-go-go-Related Gene) Channel–Drug Binding Kinetics and Multichannel Pharmacology

Zhihua Li, Sara Dutta, Jiansong Sheng et al. · Circulation Arrhythmia and Electrophysiology · 2017 · 205 citations · Full text

Medicine, Cardiology, Pharmacology +17

Comprehensive In Vitro Proarrhythmia Assay (CiPA) Update from a Cardiac Safety Research Consortium / Health and Environmental Sciences Institute / FDA Meeting

David G. Strauss, Gary A. Gintant, Zhihua Li et al. · Therapeutic Innovation & Regulatory Science · 2018 · 112 citations

Medicine, Cardiology, Pharmacology +11

Uncertainty Quantification Reveals the Importance of Data Variability and Experimental Design Considerations for in Silico Proarrhythmia Risk Assessment

Kelly C. Chang, Sara Dutta, Gary R. Mirams et al. · Frontiers in Physiology · 2017 · 105 citations · Full text

Medicine, Cardiology, Pharmacology +15

The effect of antibiotics on the gut microbiome: a metagenomics analysis of microbial shift and gut antibiotic resistance in antibiotic treated mice

Lei Xu, Anil Surathu, Isaac Raplee et al. · BMC Genomics · 2020 · 87 citations · Full text

Life Sciences, Microbiology, Antimicrobial Resistance +16

Nrf2‑dependent antioxidant response mediated the protective effect of tanshinone IIA on doxorubicin‑induced cardiotoxicity

Zhaohui Guo, Miao Yan, Lei Chen et al. · Experimental and Therapeutic Medicine · 2018 · 75 citations · Full text

Life Sciences, Cardiology, Pharmacology +17