Improving the In Silico Assessment of Proarrhythmia Risk by Combining hERG (Human Ether-à-go-go-Related Gene) Channel–Drug Binding Kinetics and Multichannel Pharmacology

Zhihua Li, Sara Dutta, Jiansong Sheng, +6

Circulation Arrhythmia and Electrophysiology

Optimization of an In silico Cardiac Cell Model for Proarrhythmia Risk Assessment

Sara Dutta, Kelly C. Chang, Kylie A. Beattie, +7

Frontiers in Physiology

Assessment of an <i>In Silico</i> Mechanistic Model for Proarrhythmia Risk Prediction Under the Ci<scp>PA</scp> Initiative

Zhihua Li, Bradley J. Ridder, Xiaomei Han, +12

Clinical Pharmacology & Therapeutics

Calcium-channel number critically influences synaptic strength and plasticity at the active zone

Jiansong Sheng, Liming He, Hongwei Zheng, +7

Nature Neuroscience

Synaptic PlasticityNeurodynamicsNeurophysiologyCalcium-channel NumberSynaptic Strength +10

Actin Is Crucial for All Kinetically Distinguishable Forms of Endocytosis at Synapses

Xin-Sheng Wu, Sung Hoon Lee, Jiansong Sheng, +7

Neuron

Molecular NeuroscienceSignal TransductionNatural SciencesEndocytic PathwayMolecular Biology +8

Mesoporous silica microcapsule-supported Ag nanoparticles fabricated via nano-assembly and its antibacterial properties

Hui Ying Yang, Yan Liu, Qianhong Shen, +4

Journal of Materials Chemistry

NanoparticlesEngineeringPolymer NanotechnologyAntibacterial ActivityEscherichia Coli +16

Uncertainty Quantification Reveals the Importance of Data Variability and Experimental Design Considerations for in Silico Proarrhythmia Risk Assessment

Kelly C. Chang, Sara Dutta, Gary R. Mirams, +8

Frontiers in Physiology

Post-fusion structural changes and their roles in exocytosis and endocytosis of dense-core vesicles

Hsueh‐Cheng Chiang, Wonchul Shin, Wei-Dong Zhao, +7

Nature Communications

Membrane FusionBiophysicsPost-fusion Structural ChangesNatural SciencesEndocytic Pathway +11

Apomorphine‐induced activation of dopamine receptors modulates FGF‐2 expression in astrocytic cultures and promotes survival of dopaminergic neurons

Aiqun Li, Xiaoying Luo, Jiansong Sheng, +11

The FASEB Journal

NeurotransmitterDopamine ReceptorsSocial SciencesNeuroinflammationStriatal Astrocytes +17

Effect and mechanism of colloidal silica sol on properties and microstructure of the hardened cement-based materials as compared to nano-silica powder with agglomerates in micron-scale

Deyu Kong, Haiwen Pan, Linhai Wang, +4

Cement and Concrete Composites

Materials ScienceCementationEngineeringMechanical PropertiesNano-silica Powder +7