Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death

Sylwia Wasiak, Rodolfo Zunino, Heidi M. McBride

The Journal of Cell Biology

MitophagySignal TransductionStable AssociationMitochondrial FunctionOrganelle Dynamic +13

Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASP

Natasha K. Hussain, Sarah Jenna, Michael Glogauer, +8

Nature Cell Biology

Protein FunctionSignal TransductionProtein AssemblyNatural SciencesEndocytic Pathway +7

Tandem MS analysis of brain clathrin-coated vesicles reveals their critical involvement in synaptic vesicle recycling

F Blondeau, Brigitte Ritter, Patrick D. Allaire, +11

Proceedings of the National Academy of Sciences

Characterization of an RNA Granule from Developing Brain

George Elvira, Sylwia Wasiak, Vanessa Blandford, +11

Molecular & Cellular Proteomics

Brain DevelopmentSubcellular FractionationCytoskeletonCellular NeurobiologyCellular Physiology +17

RVX-208, an Inducer of ApoA-I in Humans, Is a BET Bromodomain Antagonist

Kevin G. McLure, Emily M. Gesner, Laura Tsujikawa, +12

PLoS ONE

Bet Bromodomain AntagonistImmunologyApolipoprotein A-iPharmacotherapyInflammation +18

Enthoprotin

Sylwia Wasiak, Valérie Legendre‐Guillemin, Rosa Puertollano, +7

The Journal of Cell Biology

Mammalian Polynucleotide Phosphorylase Is an Intermembrane Space RNase That Maintains Mitochondrial Homeostasis

Hsiao‐Wen Chen, Robert N. Rainey, Cynthia E. Balatoni, +8

Molecular and Cellular Biology

Apabetalone (RVX-208) reduces vascular inflammation in vitro and in CVD patients by a BET-dependent epigenetic mechanism

Laura Tsujikawa, Li Fu, Shovon Das, +13

Clinical Epigenetics

RVX-208, a BET-inhibitor for treating atherosclerotic cardiovascular disease, raises ApoA-I/HDL and represses pathways that contribute to cardiovascular disease

Dean Gilham, Sylwia Wasiak, Laura Tsujikawa, +7

Atherosclerosis

InflammationMetabolic SyndromeExcess CholesterolCardiovascular DiseaseMedicine +10

The Activity of the GTPase-activating Protein CdGAP Is Regulated by the Endocytic Protein Intersectin

Sarah Jenna, Natasha K. Hussain, Eric I. Danek, +4

Journal of Biological Chemistry