Concepedia

John P. Bingham

JP

Statistics

Publications

15

Citations

621

H-Index

14

Active since

1992

Affiliations

University College London(Current)

Cancer Research UK

University of Ferrara

The Royal Free Hospital

CRUK Lung Cancer Centre of Excellence

John P. Bingham is an author at University College London specializing in medicinal chemistry, oncology, and chemotherapy.

ORCID

Publications per year

1992–2018

15

Publications

15

Pre-clinical pharmacology and mechanism of action of SG3199, the pyrrolobenzodiazepine (PBD) dimer warhead component of antibody-drug conjugate (ADC) payload tesirine

John A. Hartley, Michael Flynn, John P. Bingham et al. · Scientific Reports · 2018 · 129 citations · Full text

, , +14

Targeting of tumor cells and DNA by a chlorambucil-spermidine conjugate.

Jane L. Holley, Andrew Mather, Richard T. Wheelhouse et al. · PubMed · 1992 · 75 citations

, , +11

DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards is preserved in intact cells

J.A. Hartley, John P. Bingham, Robert L. Souhami · Nucleic Acids Research · 1992 · 59 citations · Full text

, , +14

Design, Synthesis, and Biological Activity of Hybrid Compounds between Uramustine and DNA Minor Groove Binder Distamycin A

Pier Giovanni Baraldi, Romeo Romagnoli, Antonio Entrena Guadix et al. · Journal of Medicinal Chemistry · 2002 · 58 citations

, , +15

Increased sensitivity to platinum drugs of cancer cells with acquired resistance to trabectedin

Benedetta Colmegna, Sarah Uboldi, Roberta Frapolli et al. · British Journal of Cancer · 2015 · 44 citations · Full text

, , +17

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