Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice

Ariel Halper-Stromberg, Ching-Lan Lu, Florian Klein, +13

Cell

Humanized MiceViral PersistenceNeutralizing AntibodiesHuman RetrovirusHiv-1 Latent Reservoirs +7

Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice

Pia Dosenovic, Lotta von Boehmer, Amelia Escolano, +21

Cell

Primary ImmunodeficiencyHuman RetrovirusImmunologyAntiviral ResponseAutoimmunity +4

Sequencing and cloning of antigen-specific antibodies from mouse memory B cells

Lotta von Boehmer, Cassie Liu, Sarah E. Ackerman, +4

Nature Protocols

Autoimmune DiseaseAntigen-specific AntibodiesHumoral ResponseImmunologyImmunodominance +8

Improving Neutralization Potency and Breadth by Combining Broadly Reactive HIV-1 Antibodies Targeting Major Neutralization Epitopes

Rui Kong, Mark K. Louder, Kshitij Wagh, +11

Journal of Virology

Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants

Florian Klein, Lilian Nogueira, Yoshiaki Nishimura, +17

The Journal of Experimental Medicine

An anti-PD-1–GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy

Sarah Chan, Nicole A. Belmar, Sun K. Ho, +38

Nature Cancer

A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo

Natalia T. Freund, Joshua A. Horwitz, Lilian Nogueira, +14

PLoS Pathogens

ImmunologyImmunodominanceMolecular BiologyCd4 T Cell ResponsesImmunotherapeutics +14

Lipopolysaccharide Biosynthesis without the Lipids: Recognition Promiscuity of <i>Escherichia coli</i> Heptosyltransferase I

Daniel J. Czyzyk, Cassie Liu, Erika A. Taylor

Biochemistry

Using Ligand‐Based Virtual Screening to Allosterically Stabilize the Activated State of a GPCR

Christina Taylor, Nicole B. Rockweiler, Cassie Liu, +4

Chemical Biology & Drug Design

Molecular BiologyActivated StateOptogeneticsAllosterically StabilizeMolecular Pharmacology +17

NB compounds are potent and efficacious FOXM1 inhibitors in high-grade serous ovarian cancer cells

Cassie Liu, Makenzie Vorderbruggen, Catalina Muñoz-Trujillo, +4

Journal of Ovarian Research