Mieke Nys

The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors

Mieke Nys, Eleftherios Zarkadas, Marijke Brams et al. · Nature Communications · 2022 · 55 citations · Full text

Structure of the SthK Carboxy-Terminal Region Reveals a Gating Mechanism for Cyclic Nucleotide-Modulated Ion Channels

Divya Kesters, Marijke Brams, Mieke Nys et al. · PLoS ONE · 2015 · 41 citations · Full text

Molecular Biology, Cellular Physiology, Hyperpolarization (Biology) +16

The structural basis for an on–off switch controlling Gβγ-mediated inhibition of TRPM3 channels

Marc Behrendt, Fabian Gruss, Raissa Enzeroth et al. · Proceedings of the National Academy of Sciences · 2020 · 34 citations · Full text

Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine

Mieke Nys, Eveline Wijckmans, Ana Farinha et al. · Proceedings of the National Academy of Sciences · 2016 · 32 citations · Full text

Insights into the Structural Determinants Required for High-Affinity Binding of Chiral Cyclopropane-Containing Ligands to α4β2-Nicotinic Acetylcholine Receptors: An Integrated Approach to Behaviorally Active Nicotinic Ligands

Han-Kun Zhang, J. Brek Eaton, Li-Fang Yu et al. · Journal of Medicinal Chemistry · 2012 · 28 citations · Full text

Drug Target, Molecular Pharmacology, Structural Determinants +17