PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells

Chaido Stathopoulou, Arunakumar Gangaplara, Grace Mallett, +18

Immunity

Transcriptional RegulationSignal TransductionMolecular PhysiologySignaling PathwayT-regulatory Cell +5

miR-27b*, an oxidative stress-responsive microRNA modulates nuclear factor-kB pathway in RAW 264.7 cells

Sivasubramani Thulasingam, Chandirasegaran Massilamany, Arunakumar Gangaplara, +6

Molecular and Cellular Biochemistry

Raw 264.7Microrna DetectionSmall RnaSystems BiologyMedicine +4

Type I interferon signaling attenuates regulatory T cell function in viral infection and in the tumor microenvironment

Arunakumar Gangaplara, Craig Martens, Eric Dahlstrom, +8

PLoS Pathogens

Adaptive Immune SystemT-regulatory CellImmunologyImmune RegulationImmunodominance +22

Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells

Ping‐Hsien Lee, Tori N. Yamamoto, Devikala Gurusamy, +11

The Journal of Experimental Medicine

Identification of novel mimicry epitopes for cardiac myosin heavy chain-α that induce autoimmune myocarditis in A/J mice

Chandirasegaran Massilamany, Arunakumar Gangaplara, David Steffen, +1

Cellular Immunology

InflammationCardiac MuscleAutoimmune DiseaseImmunodeficienciesA/j Mice +11

Coxsackievirus B3 infection leads to the generation of cardiac myosin heavy chain-α-reactive CD4 T cells in A/J mice

Arunakumar Gangaplara, Chandirasegaran Massilamany, Deborah M. Brown, +6

Clinical Immunology

Cardiac MusclePathogenesisViral PathogenesisImmunologyA/j Mice +9

CD47 Expression in Natural Killer Cells Regulates Homeostasis and Modulates Immune Response to Lymphocytic Choriomeningitis Virus

Pulak Ranjan Nath, Arunakumar Gangaplara, Dipasmita Pal-Nath, +6

Frontiers in Immunology

A Urinary Metabolic Signature for Multiple Sclerosis and Neuromyelitis Optica

Teklab Gebregiworgis, Helle Hvilsted Nielsen, Chandirasegaran Massilamany, +4

Journal of Proteome Research

Neurological DisorderMetabolomic ProfilingOptic NerveBioanalysisClinical Diagnosis +15

Selective deletion of Eos (Ikzf4) in T-regulatory cells leads to loss of suppressive function and development of systemic autoimmunity

Ameya Gokhale, Arunakumar Gangaplara, Maria Lopez-Occasio, +2

Journal of Autoimmunity

Autoimmune DiseaseLymphocyte DevelopmentImmune Cell DevelopmentT-regulatory CellImmunology +8

Recombinant OMP28 antigen-based indirect ELISA for serodiagnosis of bovine brucellosis

Pallab Chaudhuri, Rajeev Prasad, V. S. S. Kumar, +1

Molecular and Cellular Probes

Animal SciencePathogenesisImmunologyVeterinary SciencePathology +8