Becky Penhallow

Discovery of (<i>R</i>)-7-Cyano-2,3,4,5-tetrahydro-1-(1<i>H</i>-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1<i>H</i>-1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity

John T. Hunt, Charles Z. Ding, Roberta S. Batorsky et al. · Journal of Medicinal Chemistry · 2000 · 134 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors

Petra Ross‐Macdonald, Heshani de Silva, Qi Guo et al. · Molecular Cancer Therapeutics · 2008 · 128 citations

Life Sciences, Molecular Biology, Pharmacology +15

Selective Itk Inhibitors Block T-Cell Activation and Murine Lung Inflammation

Tai-An Lin, Kim W. McIntyre, Jagabandhu Das et al. · Biochemistry · 2004 · 113 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Characterization of BMS-911543, a functionally selective small-molecule inhibitor of JAK2

Ashok V. Purandare, Theresa McDevitt, Han Wan et al. · Leukemia · 2011 · 77 citations

Medicine, Medicinal Chemistry, Pharmacology +9

Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors

Jagabandhu Das, Joseph A. Furch, Chunjian Liu et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 75 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12