Heshani de Silva

A Landscape of Pharmacogenomic Interactions in Cancer

Francesco Iorio, Theo Knijnenburg, Daniël J. Vis et al. · Cell · 2016 · 2.2K citations · Full text

Tumor Biology, Oncology, Tumor Heterogeneity +13

Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors

Mark R. Lackner, Rachel M. Kindt, Pamela M. Carroll et al. · Cancer Cell · 2005 · 131 citations · Full text

Chemical Genetics, Rab Geranylgeranyl Transferase, Biochemistry +12

Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors

Petra Ross‐Macdonald, Heshani de Silva, Qi Guo et al. · Molecular Cancer Therapeutics · 2008 · 126 citations

Transcriptional Profiling of the Dose Response: A More Powerful Approach for Characterizing Drug Activities

Rui‐Ru Ji, Heshani de Silva, Yisheng Jin et al. · PLoS Computational Biology · 2009 · 34 citations · Full text

Transcriptional Profiling, Drug Target, Dose Response +19

Validation of the Lung Immune Prognostic Index (LIPI) as a prognostic biomarker in metastatic renal cell carcinoma

Lucía Carril-Ajuria, Pernelle Lavaud, Cécile Dalban et al. · European Journal of Cancer · 2024 · 10 citations · Full text