Concepedia

Ruth Schwab

RS

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Publications

4

Citations

475

H-Index

4

Active since

2002

Affiliations

Ludwig-Maximilians-Universität München(Current)

Ruth Schwab is an author at Ludwig-Maximilians-Universität München specializing in hematology, jak-stat signaling pathway, and signal transduction.

Top concepts

Publications per year

2002–2003

4

Publications

4

Overexpression and constitutive activation of FLT3 induces STAT5 activation in primary acute myeloid leukemia blast cells.

Karsten Spiekermann, Ksenia Bagrintseva, Ruth Schwab et al. · PubMed · 2003 · 187 citations

The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3

Karsten Spiekermann, Ralf J. Dirschinger, Ruth Schwab et al. · Blood · 2003 · 114 citations · Full text

Constitutive activation of STAT3 and STAT5 is induced by leukemic fusion proteins with protein tyrosine kinase activity and is sufficient for transformation of hematopoietic precursor cells

Karsten Spiekermann, Michael J. Pau, Ruth Schwab et al. · Experimental Hematology · 2002 · 100 citations · Full text

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Mutations in the tyrosine kinase domain of FLT3 define a new molecular mechanism of acquired drug resistance to PTK inhibitors in FLT3-ITD–transformed hematopoietic cells

Ksenia Bagrintseva, Ruth Schwab, Tobias Kohl et al. · Blood · 2003 · 74 citations · Full text

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