Charlotte Smith

BET protein targeting suppresses the PD-1/PD-L1 pathway in triple-negative breast cancer and elicits anti-tumor immune response

Guillaume P. Andrieu, Jordan Shafran, Charlotte Smith et al. · Cancer Letters · 2019 · 58 citations · Full text

Bet Protein, Breast Oncology, Cancer Immunosurveillance +9

Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation

Agata Cieślak, Guillaume Charbonnier, Melania Tesio et al. · The Journal of Experimental Medicine · 2020 · 57 citations · Full text

Lymphocyte Development, Epigenetic Change, Adaptive Immune System +26

Epigenetic analysis of patients with T-ALL identifies poor outcomes and a hypomethylating agent-responsive subgroup

Aurore Touzart, Anand Mayakonda, Charlotte Smith et al. · Science Translational Medicine · 2021 · 39 citations · Full text

Epigenetic Silencing Affects <scp>l</scp> -Asparaginase Sensitivity and Predicts Outcome in T-ALL

Aurore Touzart, Étienne Lengliné, Mehdi Latiri et al. · Clinical Cancer Research · 2019 · 37 citations · Full text

PRC2 loss of function confers a targetable vulnerability to BET proteins in T-ALL

Guillaume P. Andrieu, Milena Kohn, Mathieu Simonin et al. · Blood · 2021 · 36 citations · Full text