Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells

Órit Kollet, Ayelet Dar, Shoham Shivtiel, +9

Nature Medicine

Progenitor CellsEndosteal ComponentsBone Morphogenic ProteinMedicineBone Remodeling +8

Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy

Nina Cabezas‐Wallscheid, Florian Buettner, Pia Sommerkamp, +24

Cell

Cell RegulationMedicineAdult Stem CellStem Cell ResearchCell Proliferation +3

Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells

Arnon Dar, Amir Schajnovitz, Kfir Lapid, +18

Leukemia

Regenerative MedicineCell TherapyHematopoietic ProgenitorsCxcr4-dependent Sdf-1 ReleaseMedicine +10

Enhanced c-Met activity promotes G-CSF–induced mobilization of hematopoietic progenitor cells via ROS signaling

Melania Tesio, Karin Golan, Simona Corso, +18

Blood

MT1-MMP and RECK are involved in human CD34+ progenitor cell retention, egress, and mobilization

Yaron Vagima, Abraham Avigdor, Polina Goichberg, +15

Journal of Clinical Investigation

CD45 regulates retention, motility, and numbers of hematopoietic progenitors, and affects osteoclast remodeling of metaphyseal trabecules

Shoham Shivtiel, Órit Kollet, Kfir Lapid, +9

The Journal of Experimental Medicine

SclerostinImmunologyCytoskeletonOsteoporosisCellular Physiology +15

cAMP-induced PKCζ activation increases functional CXCR4 expression on human CD34+ hematopoietic progenitors

Polina Goichberg, Alexander Kalinkovich, Nataliya Borodovsky, +5

Blood

Functional CXCR4-Expressing Microparticles and SDF-1 Correlate with Circulating Acute Myelogenous Leukemia Cells

Alexander Kalinkovich, Sigal Tavor, Abraham Avigdor, +12

Cancer Research

c-Met and Its Ligand Hepatocyte Growth Factor/Scatter Factor Regulate Mature B Cell Survival in a Pathway Induced by CD74

Maya Gordin, Melania Tesio, Sivan Cohen, +5

The Journal of Immunology

Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation

Agata Cieślak, Guillaume Charbonnier, Melania Tesio, +16

The Journal of Experimental Medicine

Lymphocyte DevelopmentEpigenetic ChangeAdaptive Immune SystemT-regulatory CellImmune Regulation +24