Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells

Órit Kollet, Ayelet Dar, Shoham Shivtiel, +9

Nature Medicine

Progenitor CellsEndosteal ComponentsBone Morphogenic ProteinMedicineBone Remodeling +8

Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells

Arnon Dar, Amir Schajnovitz, Kfir Lapid, +18

Leukemia

Regenerative MedicineCell TherapyHematopoietic ProgenitorsCxcr4-dependent Sdf-1 ReleaseMedicine +10

S1P promotes murine progenitor cell egress and mobilization via S1P1-mediated ROS signaling and SDF-1 release

Karin Golan, Yaron Vagima, Aya Ludin, +12

Blood

CD45 regulates retention, motility, and numbers of hematopoietic progenitors, and affects osteoclast remodeling of metaphyseal trabecules

Shoham Shivtiel, Órit Kollet, Kfir Lapid, +9

The Journal of Experimental Medicine

SclerostinImmunologyCytoskeletonOsteoporosisCellular Physiology +15

Pathways Implicated in Stem Cell Migration: The SDF-1/CXCR4 Axis

Yaron Vagima, Kfir Lapid, Órit Kollet, +3

Methods in molecular biology

Physiologic corticosterone oscillations regulate murine hematopoietic stem/progenitor cell proliferation and CXCL12 expression by bone marrow stromal progenitors

Órit Kollet, Yaron Vagima, Gabriele D’Uva, +14

Leukemia

Bone Marrow FailurePhysiologic Corticosterone OscillationsCell SignalingMedicinePhysiology +9

Oestrogen signalling in white adipose progenitor cells inhibits differentiation into brown adipose and smooth muscle cells

Kfir Lapid, Ajin Lim, Deborah J. Clegg, +2

Nature Communications

Metabolic SyndromeSignal TransductionMolecular PhysiologyDevelopmental BiologyEndocrine Mechanism +10

GSK3β regulates physiological migration of stem/progenitor cells via cytoskeletal rearrangement

Kfir Lapid, Tomer Itkin, Gabriele D’Uva, +8

Journal of Clinical Investigation

CD45 regulates homing and engraftment of immature normal and leukemic human cells in transplanted immunodeficient mice

Shoham Shivtiel, Kfir Lapid, Vyacheslav Kalchenko, +6

Experimental Hematology

Cell TherapyTransplantationImmunologyLeukemic Human CellsAutoimmunity +5

Egress and mobilization of hematopoietic stem and progenitor cells

Kfir Lapid, Yaron Vagima, Órit Kollet, +1

Progenitor CellsMedicineStem Cell MobilizationHematologyStem Cell Research +6