David R. Tortolani

Two distinct actions of retinoid-receptor ligands

Jiayang Chen, John L. Clifford, C. Zusi et al. · Nature · 1996 · 196 citations

Signal Transduction, Retina, Functional Selectivity +5

Synthesis, Oral Bioavailability Determination, and in vitro Evaluation of Prodrugs of the Antiviral Agent 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA)

John E. Starrett, David R. Tortolani, Michael J. M. Hitchcock et al. · Journal of Medicinal Chemistry · 1994 · 141 citations

Synthesis and in vitro evaluation of a phosphonate prodrug: bis(pivaloyloxymethyl) 9-(2-phosphonylmethoxyethyl)adenine

John E. Starrett, David R. Tortolani, Michael J. M. Hitchcock et al. · Antiviral Research · 1992 · 120 citations

Medicinal Chemistry, Pharmaceutical Science, Biochemistry +11

Preparation of 1-(2,3-dideoxy-.beta.-D-glycero-pent-2-enofuranosyl)thymine (d4T) and 2',3'-dideoxyadenosine (ddA): general methods for the synthesis of 2',3'-olefinic and 2',3'-dideoxy nucleoside analogs active against HIV

Muzammil M. Mansuri, John E. Starrett, John A. Wos et al. · The Journal of Organic Chemistry · 1989 · 92 citations

2',3'-Dideoxy Nucleoside Analogs, Bioorganic Chemistry, Altmetric Attention Score +17

Rational design of RAR‐selective ligands revealed by RARβ crystal stucture

Pierre Germain, Sabrina Kammerer, Efrén Pérez‐Santín et al. · EMBO Reports · 2004 · 86 citations · Full text

Crystal Structure, Engineering, Rational Design +4