Prescott T. Leach

<i>Gadd45b</i> knockout mice exhibit selective deficits in hippocampus-dependent long-term memory

Prescott T. Leach, Shane G. Poplawski, Justin W. Kenney et al. · Learning & Memory · 2012 · 83 citations · Full text

Life Sciences, Genetics, Neuroscience +14

Targeted Deletion of the Mouse α2 Nicotinic Acetylcholine Receptor Subunit Gene (<i>Chrna</i>2) Potentiates Nicotine-Modulated Behaviors

Shahrdad Lotfipour, Janet S. Byun, Prescott T. Leach et al. · Journal of Neuroscience · 2013 · 69 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation

Mihirbaran Mandal, Zhaoning Zhu, Jared N. Cumming et al. · Journal of Medicinal Chemistry · 2012 · 57 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Nantenine: an antagonist of the behavioral and physiological effects of MDMA in mice

William E. Fantegrossi, Christina Lynn Kiessel, Prescott T. Leach et al. · Psychopharmacology · 2004 · 49 citations · Full text

Medicine, Neuroscience, Pharmacology +6

Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates

Mihirbaran Mandal, Yusheng Wu, Jeffrey Misiaszek et al. · Journal of Medicinal Chemistry · 2016 · 43 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11