Jacob M. Tome

Comprehensive analysis of RNA-protein interactions by high-throughput sequencing–RNA affinity profiling

Jacob M. Tome, Abdullah Ozer, John M. Pagano et al. · Nature Methods · 2014 · 138 citations · Full text

Systems Biology, Functional Genomics, Engineering +10

Single-molecule nascent RNA sequencing identifies regulatory domain architecture at promoters and enhancers

Jacob M. Tome, Nathaniel D. Tippens, John T. Lis · Nature Genetics · 2018 · 121 citations

Transcriptional Regulation, Functional Genomics, Single Cell Sequencing +9

Distinct properties and functions of CTCF revealed by a rapidly inducible degron system

Jing Luan, Guanjue Xiang, Pablo Aurelio Gómez-García et al. · Cell Reports · 2021 · 96 citations · Full text

Genetics, Molecular Biology, Ctcf Functional Diversity +17

A rapid, sensitive, scalable method for Precision Run-On sequencing (PRO-seq)

Julius Judd, Luke Wojenski, Lauren M. Wainman et al. · 2020 · 71 citations · Full text

Engineering, Genetics, Molecular Biology +26

CTCF blocks antisense transcription initiation at divergent promoters

Jing Luan, Marit W. Vermunt, Camille M. Syrett et al. · Nature Structural & Molecular Biology · 2022 · 27 citations · Full text

Chromatin, Transcriptional Regulation, Medicine +5