Atsuo Tamura

<i>In silico</i> discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras–effector interaction

Fumi Shima, Yoko Yoshikawa, Min Ye et al. · Proceedings of the National Academy of Sciences · 2013 · 294 citations · Full text

Medicine, Oncology, Pharmacology +13

Significant discrepancies between van't Hoff and calorimetric enthalpies.

Hossein Naghibi, Atsuo Tamura, Julian M. Sturtevant · Proceedings of the National Academy of Sciences · 1995 · 293 citations · Full text

Natural Sciences, Chemistry, Chemical Kinetics +14

Structural Basis for Conformational Dynamics of GTP-bound Ras Protein

Fumi Shima, Yuichi Ijiri, Shin Muraoka et al. · Journal of Biological Chemistry · 2010 · 152 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

The entropy cost of protein association

Atsuo Tamura, Peter L. Privalov · Journal of Molecular Biology · 1997 · 124 citations · Full text

Natural Sciences, Biochemistry, Biophysics +17

Solution Structure of the State 1 Conformer of GTP-bound H-Ras Protein and Distinct Dynamic Properties between the State 1 and State 2 Conformers

Mitsugu Araki, Fumi Shima, Yoko Yoshikawa et al. · Journal of Biological Chemistry · 2011 · 109 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17