Gregory J. Withbroe

Streamlined Synthesis of the Bippyphos Family of Ligands and Cross-Coupling Applications

Gregory J. Withbroe, Robert A. Singer, Janice E. Sieser · Organic Process Research & Development · 2008 · 107 citations

Combinatorial Chemistry, Cross-coupling Reaction, Engineering +13

A Highly Selective, Non-Hydantoin, Non-Carboxylic Acid Inhibitor of Aldose Reductase with Potent Oral Activity in Diabetic Rat Models:  6-(5-Chloro-3-methylbenzofuran- 2-sulfonyl)-2-<i>H</i>-pyridazin-3-one

Banavara L. Mylari, Sandra J. Armento, David A. Beebe et al. · Journal of Medicinal Chemistry · 2003 · 68 citations · Full text

Oral Bioavailability, Aldo-keto Reductase, Glycobiology +17

Development of an Efficient Pd-Catalyzed Coupling Process for Axitinib

Brian P. Chekal, Steven M. Guinness, Brett M. Lillie et al. · Organic Process Research & Development · 2013 · 66 citations

Materials Science, Migita Coupling, Chemical Engineering +9

A Novel Series of Non-Carboxylic Acid, Non-Hydantoin Inhibitors of Aldose Reductase with Potent Oral Activity in Diabetic Rat Models:  6-(5-Chloro-3-methylbenzofuran-2-sulfonyl)-2<i>H</i>-pyridazin-3-one and Congeners

Banavara L. Mylari, Sandra J. Armento, David A. Beebe et al. · Journal of Medicinal Chemistry · 2005 · 65 citations · Full text

Medicinal Chemistry, Aldo-keto Reductase, Biochemistry +15

A Sorbitol Dehydrogenase Inhibitor of Exceptional in Vivo Potency with a Long Duration of Action:  1-(<i>R</i>)-{4-[4-(4,6-Dimethyl[1,3,5]triazin-2-yl)- 2<i>R</i>,6<i>S</i>-dimethylpiperazin-1-yl]pyrimidin-2- yl}ethanol

Banavara L. Mylari, Peter J. Oates, William J. Zembrowski et al. · Journal of Medicinal Chemistry · 2002 · 19 citations · Full text

Bioorganic Chemistry, Gastrointestinal Pharmacology, Glycobiology +20