Darren Plant

Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides

Rachel H. Clare, Catherine Bardelle, Paul Harper et al. · Nature Communications · 2018 · 130 citations · Full text

Pharmacy, Infectious Diseases, Medicinal Chemistry +17

Discovery of Imidazo[1,2-<i>a</i>]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis

Subramanyam J. Tantry, Shankar D. Markad, Vikas Shinde et al. · Journal of Medicinal Chemistry · 2017 · 126 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery and Optimization of Allosteric Inhibitors of Mutant Isocitrate Dehydrogenase 1 (R132H IDH1) Displaying Activity in Human Acute Myeloid Leukemia Cells

Stuart Jones, Jonathan Ahmet, Kelly Ayton et al. · Journal of Medicinal Chemistry · 2016 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Advancing automation in high-throughput screening: Modular unguarded systems enable adaptable drug discovery

Catherine S. Hansel, Darren Plant, Geoffrey A. Holdgate et al. · Drug Discovery Today · 2022 · 26 citations

Pharmacy, Pharmacology, Drug Discovery +11

High-Throughput Screening of RNA Polymerase Inhibitors Using a Fluorescent UTP Analog

Jyothi Bhat, Rajendra Rane, Suresh Solapure et al. · SLAS DISCOVERY · 2006 · 25 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15