Rongzhen Lu

The oncology drug elesclomol selectively transports copper to the mitochondria to induce oxidative stress in cancer cells

Masazumi Nagai, Nha Huu Vo, Luisa Shin Ogawa et al. · Free Radical Biology and Medicine · 2012 · 330 citations

Mitochondrial Function, Biochemistry, Medicine +10

A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer

Rongzhen Lu, Huw M. Nash, Gregory L. Verdine · Current Biology · 1997 · 320 citations · Full text

Chromatin, Genome Instability, Dna Damage +12

The critical active-site amine of the human 8-oxoguanine DNA glycosylase, hOgg1: direct identification, ablation and chemical reconstitution

Huw M. Nash, Rongzhen Lu, William S. Lane et al. · Chemistry & Biology · 1997 · 169 citations · Full text

Critical Active-site Amine, Nucleic Acid Chemistry, Direct Identification +8

Selective abrogation of Th1 response by STA-5326, a potent IL-12/IL-23 inhibitor

Yumiko Wada, Rongzhen Lu, Dan Zhou et al. · Blood · 2006 · 88 citations · Full text

Novel indolizine compounds as potent inhibitors of phosphodiesterase IV (PDE4): structure–activity relationship

Shoujun Chen, Zhiqiang Xia, Masazumi Nagai et al. · MedChemComm · 2010 · 36 citations

Structure–activity Relationship, Phosphodiesterase Iv, Chemical Biology +19