Huanyao Gao

Metabolic regulation of homologous recombination repair by MRE11 lactylation

Yuping Chen, Jinhuan Wu, Linhui Zhai et al. · Cell · 2023 · 329 citations · Full text

Metabolic Regulation, Genome Instability, Medicine +1

<i>Arabidopsis thaliana</i> Nfu2 Accommodates [2Fe-2S] or [4Fe-4S] Clusters and Is Competent for <i>in Vitro</i> Maturation of Chloroplast [2Fe-2S] and [4Fe-4S] Cluster-Containing Proteins

Huanyao Gao, Subramanian Sowmya, Jérémy Couturier et al. · Biochemistry · 2013 · 81 citations · Full text

METTL16 antagonizes MRE11-mediated DNA end resection and confers synthetic lethality to PARP inhibition in pancreatic ductal adenocarcinoma

Xiangyu Zeng, Fei Zhao, Gaofeng Cui et al. · Nature Cancer · 2022 · 64 citations

Oncology, Parp Inhibition, Pancreatic Cancer +9

ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection

Fei Zhao, Wootae Kim, Huanyao Gao et al. · Nature Cell Biology · 2021 · 46 citations

Chromatin, Genome Instability, End Resection +3

SUMOylation of HNRNPA2B1 modulates RPA dynamics during unperturbed replication and genotoxic stress responses

Shouhai Zhu, Jing Hou, Huanyao Gao et al. · Molecular Cell · 2023 · 38 citations · Full text

Reductive Stress, Genome Instability, Systems Biology +9