María J. Comin

Preclinical Development of Novel Rac1-GEF Signaling Inhibitors using a Rational Design Approach in Highly Aggressive Breast Cancer Cell Lines

Georgina A. Cardama, María J. Comin, Leandro Hornos et al. · Anti-Cancer Agents in Medicinal Chemistry · 2013 · 86 citations · Full text

Medicine, Oncology, Pharmacology +17

A Conformationally Locked Analogue of the Anti-HIV Agent Stavudine. An Important Correlation between Pseudorotation and Maximum Amplitude

Yongseok Choi, Clifford George, María J. Comin et al. · Journal of Medicinal Chemistry · 2003 · 54 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +15

Evaluation of the antiviral activity of natural sulfated polyhydroxysteroids and their synthetic derivatives and analogs

María J. Comin, Marta S. Maier, Alejandro J. Roccatagliata et al. · Steroids · 1999 · 52 citations

Pharmacy, Infectious Diseases, Medicinal Chemistry +15

Proapoptotic and antiinvasive activity of Rac1 small molecule inhibitors on malignant glioma cells

Daniel E. Gómez, Georgina A. Cardama, Nazareno González et al. · OncoTargets and Therapy · 2014 · 45 citations · Full text

Life Sciences, Oncology, Pharmacology +16

Understanding How the Herpes Thymidine Kinase Orchestrates Optimal Sugar and Nucleobase Conformations To Accommodate Its Substrate at the Active Site:  A Chemical Approach

Víctor E. Márquez, Yongseok Choi, María J. Comin et al. · Journal of the American Chemical Society · 2005 · 40 citations

Life Sciences, Biochemistry, Molecular Biology +12