Hironobu Hiyoshi

In Vitro and In Vivo Activities of E5700 and ER-119884, Two Novel Orally Active Squalene Synthase Inhibitors, against <i>Trypanosoma cruzi</i>

Julio A. Urbina, Juan Luís Concepción, Aura Caldera et al. · Antimicrobial Agents and Chemotherapy · 2004 · 89 citations · Full text

Trypanosoma Cruzi, Medicinal Chemistry, Bioorganic Chemistry +15

Effect of ER-27856, a novel squalene synthase inhibitor, on plasma cholesterol in rhesus monkeys: comparison with 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors

Hironobu Hiyoshi, Mamoru Yanagimachi, Masashi Ito et al. · Journal of Lipid Research · 2000 · 63 citations · Full text

The novel and orally active thrombin receptor antagonist E5555 (Atopaxar) inhibits arterial thrombosis without affecting bleeding time in guinea pigs

Motoji Kogushi, Toshiyuki Matsuoka, Tsutomu Kawata et al. · European Journal of Pharmacology · 2011 · 47 citations

Inflammation, Thrombosis, Cardiovascular Disease +12

Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes

Hironobu Hiyoshi, Mamoru Yanagimachi, Masashi Ito et al. · Journal of Lipid Research · 2003 · 46 citations · Full text

Effect of the acyl-CoA:cholesterol acyltransferase inhibitor, E5324, on experimental atherosclerosis in rabbits

Hiroshi Tanaka, Issei Ohtsuka, Motoji Kogushi et al. · Atherosclerosis · 1994 · 33 citations

Inflammation, Metabolic Syndrome, Thrombosis +15