Tsutomu Kawata

E5531, a Pure Endotoxin Antagonist of High Potency

William J. Christ, Osamu Asano, Andrea L. C. Robidoux et al. · Science · 1995 · 321 citations

Pharmacotherapy, Viable Escherichia Coli, Drug Resistance +16

Inhibition of Endotoxin Response by E5564, a Novel Toll-Like Receptor 4-Directed Endotoxin Antagonist

Maureen Mullarkey, Jeffrey Rose, John R. Bristol et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 290 citations

Simultaneous Blocking of Human Toll-Like Receptors 2 and 4 Suppresses Myeloid Dendritic Cell Activation Induced by<i>Mycobacterium bovis</i>Bacillus Calmette-Guerin Peptidoglycan

Junji Uehori, Misako Matsumoto, Shoutaro Tsuji et al. · Infection and Immunity · 2003 · 157 citations · Full text

2-Alkynyl-8-aryl-9-methyladenines as Novel Adenosine Receptor Antagonists:  Their Synthesis and Structure−Activity Relationships toward Hepatic Glucose Production Induced via Agonism of the A_2BReceptor

Hitoshi Harada, Osamu Asano, Yorihisa Hoshino et al. · Journal of Medicinal Chemistry · 2000 · 111 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +13

Functional characterization of the adenosine receptor contributing to glycogenolysis and gluconeogenesis in rat hepatocytes

Nobuyuki Yasuda, Takashi Inoue, Tatsuo Horizoe et al. · European Journal of Pharmacology · 2003 · 67 citations

Cell Physiology, Molecular Physiology, Signal Transduction +14