Jeffrey Rose

The Extra Domain A of Fibronectin Activates Toll-like Receptor 4

Yoshinori Okamura, Michiko Watari, Elliot S. Jerud et al. · Journal of Biological Chemistry · 2001 · 1.2K citations · Full text

Tlr4 Accessory Protein, Innate Immune System, Immunology +19

E5531, a Pure Endotoxin Antagonist of High Potency

William J. Christ, Osamu Asano, Andrea L. C. Robidoux et al. · Science · 1995 · 321 citations

Pharmacotherapy, Viable Escherichia Coli, Drug Resistance +16

Inhibition of Endotoxin Response by E5564, a Novel Toll-Like Receptor 4-Directed Endotoxin Antagonist

Maureen Mullarkey, Jeffrey Rose, John R. Bristol et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 290 citations

Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo

Marc S. Lamphier, Wanjun Zheng, Eicke Latz et al. · Molecular Pharmacology · 2013 · 139 citations

Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria

Bernardo S. Franklin, Sally T. Ishizaka, Marc S. Lamphier et al. · Proceedings of the National Academy of Sciences · 2011 · 118 citations

Innate Immune System, Immunology, Cell Death +17