Brooke M. Rock

Preclinical development and phase 1 trial of a novel siRNA targeting lipoprotein(a)

Michael J. Koren, Patrick M. Moriarty, Seth J. Baum et al. · Nature Medicine · 2022 · 218 citations

Translational Medicine, Preclinical Development, Medicine +6

SLC46A3 Is Required to Transport Catabolites of Noncleavable Antibody Maytansine Conjugates from the Lysosome to the Cytoplasm

Kevin J. Hamblett, Allison P. Jacob, Jesse L. Gurgel et al. · Cancer Research · 2015 · 128 citations

Protein Secretion, Drug Targeting, Natural Sciences +15

Characterization of Ritonavir-Mediated Inactivation of Cytochrome P450 3A4

Brooke M. Rock, Shawna Hengel, Dan A. Rock et al. · Molecular Pharmacology · 2014 · 93 citations

Modeling the CRL4A ligase complex to predict target protein ubiquitination induced by cereblon-recruiting PROTACs

Nan Bai, Kristin M. Riching, Aman Makaju et al. · Journal of Biological Chemistry · 2022 · 78 citations · Full text

Protein Assembly, Molecular Biology, Target Protein Ubiquitination +20

Intact mass analysis of monoclonal antibodies by capillary electrophoresis—Mass spectrometry

Mei Han, Brooke M. Rock, Josh T. Pearson et al. · Journal of Chromatography B · 2015 · 77 citations

Capillary Electrophoresis, Intact Mass Analysis, Medicine +12