Ahmed M. Gouda

Design and synthesis of novel quinoline/chalcone/1,2,4-triazole hybrids as potent antiproliferative agent targeting EGFR and BRAFV600E kinases

Aliaa M. Mohassab, Heba A. Hassan, Dalia Abdelhamid et al. · Bioorganic Chemistry · 2020 · 111 citations

Combinatorial Chemistry, Medicinal Chemistry, Potent Antiproliferative Agent +8

Design and synthesis of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as antiproliferative EGFR and BRAFV600E dual inhibitors

Lamya H. Al-Wahaibi, Ahmed M. Gouda, Ola F. Abou‐Ghadir et al. · Bioorganic Chemistry · 2020 · 75 citations

Medicinal Chemistry, Natural Sciences, Antiproliferative Egfr +9

Optimization of pyrrolizine-based Schiff bases with 4-thiazolidinone motif: Design, synthesis and investigation of cytotoxicity and anti-inflammatory potency

Ahmed M. Shawky, Mohammed A. S. Abourehab, Ashraf N. Abdalla et al. · European Journal of Medicinal Chemistry · 2019 · 67 citations · Full text

Anti-inflammatory Potency, Combinatorial Chemistry, Medicinal Chemistry +11

Design, synthesis, and biological evaluation of novel EGFR inhibitors containing 5-chloro-3-hydroxymethyl-indole-2-carboxamide scaffold with apoptotic antiproliferative activity

Fatma A. Mohamed, Hesham A. M. Gomaa, Omnia M. Hendawy et al. · Bioorganic Chemistry · 2021 · 67 citations

Medicinal Chemistry, Apoptotic Antiproliferative Activity, Novel Egfr Inhibitors +10

Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities

Hesham A. M. Gomaa, Mohamed E. Shaker, Sami I. Alzarea et al. · Bioorganic Chemistry · 2022 · 57 citations

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +10