Hesham A. M. Gomaa

Design, synthesis, and antibacterial evaluation of new quinoline-1,3,4-oxadiazole and quinoline-1,2,4-triazole hybrids as potential inhibitors of DNA gyrase and topoisomerase IV

Heba A. Hofny, Mamdouh F. A. Mohamed, Hesham A. M. Gomaa et al. · Bioorganic Chemistry · 2021 · 79 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

5-Chlorobenzofuran-2-carboxamides: From allosteric CB1 modulators to potential apoptotic antitumor agents

Bahaa G. M. Youssif, Ashraf M. Mohamed, Essam Eldin A. Osman et al. · European Journal of Medicinal Chemistry · 2019 · 74 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Design, synthesis, and biological evaluation of novel EGFR inhibitors containing 5-chloro-3-hydroxymethyl-indole-2-carboxamide scaffold with apoptotic antiproliferative activity

Fatma A. Mohamed, Hesham A. M. Gomaa, Omnia M. Hendawy et al. · Bioorganic Chemistry · 2021 · 69 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Novel aryl carboximidamide and 3-aryl-1,2,4-oxadiazole analogues of naproxen as dual selective COX-2/15-LOX inhibitors: Design, synthesis and docking studies

Bahaa G. M. Youssif, Mamdouh F. A. Mohamed, Mohammad M. Al‐Sanea et al. · Bioorganic Chemistry · 2019 · 61 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities

Hesham A. M. Gomaa, Mohamed E. Shaker, Sami I. Alzarea et al. · Bioorganic Chemistry · 2022 · 59 citations

Pharmacy, Medicinal Chemistry, Oncology +16