Christopher E. Rudd

The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes.

Christopher E. Rudd, James M. Trevillyan, J D Dasgupta et al. · Proceedings of the National Academy of Sciences · 1988 · 719 citations · Full text

Immunology, Molecular Biology, Immunodominance +21

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

Yu‐Hwa Huang, Chen Zhu, Yasuyuki Kondo et al. · Nature · 2014 · 703 citations

Tim-3-mediated Tolerance, Signal Transduction, Physiology +7

Reversal of the TCR Stop Signal by CTLA-4

Helga Schneider, Jos Downey, Andrew Smith et al. · Science · 2006 · 599 citations

Radio Frequency, Lymphocyte Development, Adaptive Immune System +22

The CD28-Related Molecule ICOS Is Required for Effective T Cell–Dependent Immune Responses

Anthony J. Coyle, Sophie M. Lehar, Clare M. Lloyd et al. · Immunity · 2000 · 512 citations · Full text

Adaptive Immune System, Immune Cell Development, Immunology +10

The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex.

Elizabeth K. Barber, J D Dasgupta, Stuart F. Schlossman et al. · Proceedings of the National Academy of Sciences · 1989 · 452 citations · Full text

T-regulatory Cell, Immunology, Cd3 Complex +18