Jessica D. Rosarda

Metabolically Activated Proteostasis Regulators Protect against Glutamate Toxicity by Activating NRF2

Jessica D. Rosarda, Kelsey R Baron, Kayla Nutsch et al. · ACS Chemical Biology · 2021 · 36 citations · Full text

Glutamate Toxicity, Activating Nrf2, Lipid Peroxidation +21

Imbalanced unfolded protein response signaling contributes to 1-deoxysphingolipid retinal toxicity

Jessica D. Rosarda, Sarah Giles, Sarah Harkins‐Perry et al. · Nature Communications · 2023 · 30 citations · Full text

Pharmacologic activation of a compensatory integrated stress response kinase promotes mitochondrial remodeling in PERK-deficient cells

Valerie Perea, Kelsey R Baron, Vivian Dolina et al. · Cell chemical biology · 2023 · 26 citations · Full text

Reductive Stress, Mitophagy, Pharmacologic Activation +10

Expression of Amyloidogenic Transthyretin Drives Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease

Richard M. Giadone, Derek C. Liberti, Taylor Matte et al. · Stem Cell Reports · 2020 · 24 citations · Full text

A library of ATTR amyloidosis patient-specific induced pluripotent stem cells for disease modelling and <i>in vitro</i> testing of novel therapeutics

Richard M. Giadone, Jessica D. Rosarda, Prithvi Reddy Akepati et al. · Amyloid · 2018 · 19 citations · Full text

Engineering, Disease Gene Identification, Biomedical Engineering +19