Kayla Nutsch

YAP-dependent proliferation by a small molecule targeting annexin A2

Sophia Z. Shalhout, Pengyu Yang, Edyta M. Grzelak et al. · Nature Chemical Biology · 2021 · 81 citations

Protein Function, Signaling Pathway, Annexin A2 +4

TERT activation targets DNA methylation and multiple aging hallmarks

Hong Seok Shim, Jonathan Iaconelli, Xiaoying Shang et al. · Cell · 2024 · 73 citations · Full text

Chromatin, Medicine, Genetics +6

Metabolically Activated Proteostasis Regulators Protect against Glutamate Toxicity by Activating NRF2

Jessica D. Rosarda, Kelsey R Baron, Kayla Nutsch et al. · ACS Chemical Biology · 2021 · 36 citations · Full text

Glutamate Toxicity, Activating Nrf2, Lipid Peroxidation +21

S-lactoyl modification of KEAP1 by a reactive glycolytic metabolite activates NRF2 signaling

Yeonjin Ko, Mannkyu Hong, Seungbeom Lee et al. · Proceedings of the National Academy of Sciences · 2023 · 36 citations · Full text

Cysteine Sensor Residues, Lipid Peroxidation, Cell Death +17

Succinylation of a KEAP1 sensor lysine promotes NRF2 activation

Lara Ibrahim, Caroline Stanton, Kayla Nutsch et al. · Cell chemical biology · 2023 · 26 citations · Full text

Signal Transduction, Molecular Physiology, Biochemistry +4