Sam D. Molyneux

Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression

Isaac S. Harris, Aislinn E. Treloar, Satoshi Inoue et al. · Cancer Cell · 2015 · 948 citations · Full text

Reductive Stress, Tumor Biology, Chemoprevention Strategy +10

BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival

Chiara Gorrini, Pegah S. Baniasadi, Isaac S. Harris et al. · The Journal of Experimental Medicine · 2013 · 281 citations · Full text

Cell Death, Cancer Biology, Redox Biology +18

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis

Branden S. Moriarity, George M. Otto, Eric P. Rahrmann et al. · Nature Genetics · 2015 · 244 citations

Tumor Biology, Developmental Biology, Somatic Variant +9

Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state

Masayuki Shimoda, Simona Principe, Hartland W. Jackson et al. · Nature Cell Biology · 2014 · 189 citations

Caf-like Cell State, Cell Lineage, Signal Transduction +12

Notch Activation by the Metalloproteinase ADAM17 Regulates Myeloproliferation and Atopic Barrier Immunity by Suppressing Epithelial Cytokine Synthesis

Aditya Murthy, Yang Shao, Swami Narala et al. · Immunity · 2012 · 123 citations · Full text

Inflammation, Cytokine, Allergy +10