Subunit Composition, Protein Interactions, and Structures of the Mammalian Brain sec6/8 Complex and Septin Filaments

Shu-Chan Hsu, Christopher D. Hazuka, Robyn Roth, +3

Neuron

Molecular Basis of Valine-Citrulline-PABC Linker Instability in Site-Specific ADCs and Its Mitigation by Linker Design

Magdalena Dorywalska, Russell G. Dushin, Ludivine Moine, +15

Molecular Cancer Therapeutics

Molecular BiologyChemical BiologyAntibody EngineeringAnti-cancer AgentValine-citrulline-pabc Linker Instability +16

The sec6/8 Complex Is Located at Neurite Outgrowth and Axonal Synapse-Assembly Domains

Christopher D. Hazuka, Davide Foletti, Shu-Chan Hsu, +3

Journal of Neuroscience

Protein SecretionSynapse FormationPlasma Membrane LocalizationMolecular BiologyCytoskeleton +17

Vesicle-associated Membrane Protein 4 is Implicated in<i>Trans</i>-Golgi Network Vesicle Trafficking

Martin Steegmaier, Judith Klumperman, Davide Foletti, +2

Molecular Biology of the Cell

Molecular BiologyCellular PhysiologyElectron MicroscopyEndocytic PathwaySecretory Granules +16

Effect of Attachment Site on Stability of Cleavable Antibody Drug Conjugates

Magdalena Dorywalska, Pavel Strop, Jody A. Melton-Witt, +18

Bioconjugate Chemistry

Dynamics of Tubulovesicular Recycling Endosomes in Hippocampal Neurons

Rytis Prekeris, Davide Foletti, Richard H. Scheller

Journal of Neuroscience

Developmental BiologyRound-oval Stationary OrganellesMedicineCellular PolarityEndocytic Pathway +9

High-Throughput Epitope Binning Assays on Label-Free Array-Based Biosensors Can Yield Exquisite Epitope Discrimination That Facilitates the Selection of Monoclonal Antibodies with Functional Activity

Yasmina Abdiche, Adam Miles, Josh Eckman, +5

PLoS ONE

Identical EpitopeImmunocytochemical TechniqueEngineeringEpitope Binning AssaysImmunology +20

Phosphorylated Syntaxin 1 Is Localized to Discrete Domains Along a Subset of Axons

Davide Foletti, Richard Lin, Michael Finley, +1

Journal of Neuroscience

Discrete DomainsMolecular BiologySyntaxin 1Total SyntaxinCellular Neurobiology +15

Mechanism of Action and In Vivo Efficacy of a Human-Derived Antibody against Staphylococcus aureus α-Hemolysin

Davide Foletti, Pavel Strop, Lee Shaughnessy, +10

Journal of Molecular Biology

Human-derived AntibodyMicrobial PathogensMedicineImmunologyImmunodominance +9

Characterization of the human CALM2 calmodulin gene and comparison of the transcriptional activity of CALM1, CALM2 and CALMS

Sonja L. Toutenhoofd, Davide Foletti, Roland Wicki, +4

Cell Calcium

Transcriptional RegulationGeneticsGene StructureGene RegulationGene Characterization +7