Russell G. Dushin

Location Matters: Site of Conjugation Modulates Stability and Pharmacokinetics of Antibody Drug Conjugates

Pavel Strop, Shu‐Hui Liu, Magdalena Dorywalska et al. · Chemistry & Biology · 2013 · 498 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

A general approach to site-specific antibody drug conjugates

Feng Tian, Yingchun Lu, Anthony Manibusan et al. · Proceedings of the National Academy of Sciences · 2014 · 317 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

Caveolae-Mediated Endocytosis as a Novel Mechanism of Resistance to Trastuzumab Emtansine (T-DM1)

Matthew Sung, Xingzhi Tan, Bingwen Lu et al. · Molecular Cancer Therapeutics · 2017 · 208 citations

Medicine, Oncology, Pharmacology +17

Molecular Basis of Valine-Citrulline-PABC Linker Instability in Site-Specific ADCs and Its Mitigation by Linker Design

Magdalena Dorywalska, Russell G. Dushin, Ludivine Moine et al. · Molecular Cancer Therapeutics · 2016 · 206 citations

Pharmacy, Molecular Biology, Pharmacology +17

A PTK7-targeted antibody-drug conjugate reduces tumor-initiating cells and induces sustained tumor regressions

Marc Damelin, Alexander J. Bankovich, Jeffrey Bernstein et al. · Science Translational Medicine · 2017 · 157 citations

Pharmacy, Molecular Pharmaceutics, Oncology +16