Russell G. Dushin

Location Matters: Site of Conjugation Modulates Stability and Pharmacokinetics of Antibody Drug Conjugates

Pavel Strop, Shu‐Hui Liu, Magdalena Dorywalska et al. · Chemistry & Biology · 2013 · 486 citations

Location Matters, Drug Targeting, Medicine +10

A general approach to site-specific antibody drug conjugates

Feng Tian, Yingchun Lu, Anthony Manibusan et al. · Proceedings of the National Academy of Sciences · 2014 · 309 citations · Full text

Medicinal Chemistry, Biochemistry, Polymer-drug Conjugate +15

Molecular Basis of Valine-Citrulline-PABC Linker Instability in Site-Specific ADCs and Its Mitigation by Linker Design

Magdalena Dorywalska, Russell G. Dushin, Ludivine Moine et al. · Molecular Cancer Therapeutics · 2016 · 199 citations

Molecular Biology, Chemical Biology, Antibody Engineering +18

Caveolae-Mediated Endocytosis as a Novel Mechanism of Resistance to Trastuzumab Emtansine (T-DM1)

Matthew Sung, Xingzhi Tan, Bingwen Lu et al. · Molecular Cancer Therapeutics · 2017 · 196 citations

A PTK7-targeted antibody-drug conjugate reduces tumor-initiating cells and induces sustained tumor regressions

Marc Damelin, Alexander J. Bankovich, Jeffrey Bernstein et al. · Science Translational Medicine · 2017 · 154 citations