Location Matters: Site of Conjugation Modulates Stability and Pharmacokinetics of Antibody Drug Conjugates

Pavel Strop, Shu‐Hui Liu, Magdalena Dorywalska, +26

Chemistry & Biology

Location MattersDrug TargetingMedicineImmunologyAntibody Screening +8

Studies of a human T lymphocyte antigen recognized by a monoclonal antibody.

Edgar G. Engleman, R Warnke, Robert I. Fox, +3

Proceedings of the National Academy of Sciences

HistocompatibilityLaboratory ImmunologyT-regulatory CellImmunologyImmune Regulation +15

The addition of adenovirus type 5 region E3 enables calydon virus 787 to eliminate distant prostate tumor xenografts.

D C Yu, Yu Chen, Michaela Su-Fern Seng, +2

PubMed

UrologyRegion E3Tail Vein InjectionMedicinePathology +13

A human thymus-leukemia antigen defined by hybridoma monoclonal antibodies.

Ronald Levy, Jeanette Dilley, Robert I. Fox, +1

Proceedings of the National Academy of Sciences

Lymphoid NeoplasiaHybridoma Monoclonal AntibodiesMalignant Blood DisorderImmunologyHematology +10

Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration

Jindong Ding, Lincoln V. Johnson, Rolf Herrmann, +16

Proceedings of the National Academy of Sciences

Antitumor synergy of CV787, a prostate cancer-specific adenovirus, and paclitaxel and docetaxel.

Dechao Yu, Yu Chen, Jeanette Dilley, +7

PubMed

Tumor BiologyParticles Cv787MedicineProstate Cancer-specific AdenovirusPharmacology +13

Mouse × human heterohybridomas as fusion partners with human B cell tumors

William L. Carroll, K Thielemans, Jeanette Dilley, +1

Journal of Immunological Methods

Lymphoid NeoplasiaMedicineImmunologyFusion PartnersCancer Biology +2

CV706, a prostate cancer-specific adenovirus variant, in combination with radiotherapy produces synergistic antitumor efficacy without increasing toxicity.

Yu Chen, Theodore L. DeWeese, Jeanette Dilley, +13

PubMed

Synergistic Antitumor EfficacyRadiation MedicineCancer-associated VirusMedicineVirus Burst Size +10

Immunologic Phenotype in 30 Patients with Diffuse Large-Cell Lymphoma

Roger A. Warnke, Richard A. Miller, Thomas M. Grogan, +3

New England Journal of Medicine

A single monoclonal antibody identifies T-cell lineage of childhood lymphoid malignancies

M Link, R Warnke, J Finlay, +4

Blood