Mutations in HFE2 cause iron overload in chromosome 1q–linked juvenile hemochromatosis

George Papanikolaou, Mark Samuels, E H Ludwig, +21

Nature Genetics

Juvenile HemochromatosisHeme HomeostasisIron MetabolismGeneticsHematology +6

Loss‐of‐function mutations in the Na _v 1.7 gene underlie congenital indifference to pain in multiple human populations

Y. Paul Goldberg, Julie MacFarlane, ML MacDonald, +26

Clinical Genetics

β-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment

Liam R. Brunham, Janine K. Kruit, Terry D. Pape, +9

Nature Medicine

Metabolic SyndromeInsulin SignalingDiabetes ManagementInsulin ManagementPhysiology +9

A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans

Víctor Acuña-Alonzo, María Teresa Flores-Dorantes, Janine K. Kruit, +41

Human Molecular Genetics

Identification of a Novel Gene (HSN2) Causing Hereditary Sensory and Autonomic Neuropathy Type II through the Study of Canadian Genetic Isolates

Ronald G. Lafrenière, Marcia L.E. MacDonald, Marie‐Pierre Dubé, +23

The American Journal of Human Genetics

Mendelian DisorderNovel GeneGenetic DisorderGeneticsNeurology +7

Accurate Prediction of the Functional Significance of Single Nucleotide Polymorphisms and Mutations in the ABCA1 Gene

Liam R. Brunham, Roshni R. Singaraja, Terry D. Pape, +3

PLoS Genetics

Phenotypic VariationGeneticsHuman PolymorphismMolecular GeneticsDisease Gene Identification +19

Tissue-Specific Induction of Intestinal ABCA1 Expression With a Liver X Receptor Agonist Raises Plasma HDL Cholesterol Levels

Liam R. Brunham, Janine K. Kruit, Terry D. Pape, +3

Circulation Research

InflammationMetabolic SyndromeOxysterolHepatologyMedicine +11

Genetic structure of yellow cedar (<i>Chamaecyparis nootkatensis</i>)

Carol Ritland, Terry D. Pape, Kermit Ritland

Canadian Journal of Botany

BiologyGenetic DiversityBiodiversityConservation GeneticsPhylogenetics +11

Cross-species characterization of the ALS2 gene and analysis of its pattern of expression in development and adulthood

Rebecca S. Devon, Claudia Schwab, Justin D. Topp, +11

Neurobiology of Disease

BiologyNeurodegenerative DiseasesAmyotrophic Lateral SclerosisDevelopmental BiologyGenetic Disorder +9

Genetic structure of yellow cedar (&lt;i&gt;Chamaecyparis nootkatensis&lt;/i&gt;)

Carol Ritland, Terry D. Pape, Kermit Ritland

Canadian Journal of Botany

BiologyGenetic DiversityPhylogeneticsBotanyMolecular Ecology +7