Hayley E. Tyrer

Preclinical development of an oral anti- <i>Wolbachia</i> macrolide drug for the treatment of lymphatic filariasis and onchocerciasis

Mark J. Taylor, Thomas W von Geldern, Louise Ford et al. · Science Translational Medicine · 2019 · 85 citations · Full text

Medicine, Infectious Diseases, Pharmacology +17

Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis

Ghaith Aljayyoussi, Hayley E. Tyrer, Louise Ford et al. · Scientific Reports · 2017 · 78 citations · Full text

Veterinary Medicine, Infectious Diseases, Pharmacology +17

A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasis

Alice Halliday, Ana F. Guimaraes, Hayley E. Tyrer et al. · Parasites & Vectors · 2014 · 66 citations · Full text

Veterinary Medicine, Infectious Diseases, Veterinary Parasitology +13

HIF–VEGF Pathways Are Critical for Chronic Otitis Media in Junbo and Jeff Mouse Mutants

Michael Cheeseman, Hayley E. Tyrer, Debbie Williams et al. · PLoS Genetics · 2011 · 64 citations · Full text

Medicine, Otolaryngology, Surgery +17

Albendazole and antibiotics synergize to deliver short-course anti- <i>Wolbachia</i> curative treatments in preclinical models of filariasis

Joseph D. Turner, Raman Sharma, Ghaith Al Jayoussi et al. · Proceedings of the National Academy of Sciences · 2017 · 57 citations · Full text

Pharmacy, Infectious Diseases, Pharmacology +17