Christina Schönherr

Anaplastic Lymphoma Kinase (ALK) regulates initiation of transcription of MYCN in neuroblastoma cells

Christina Schönherr, Kristina Ruuth, Sattu Kamaraj et al. · Oncogene · 2012 · 122 citations

Tumor Biology, Signaling Pathway, Cell Regulation +10

The kinase ALK stimulates the kinase ERK5 to promote the expression of the oncogene MYCN in neuroblastoma

Ganesh Umapathy, Abeer El Wakil, Barbara Witek et al. · Science Signaling · 2014 · 85 citations

Appearance of the Novel Activating F1174S ALK Mutation in Neuroblastoma Correlates with Aggressive Tumor Progression and Unresponsiveness to Therapy

Tommy Martinsson, Therése Eriksson, Jonas Abrahamsson et al. · Cancer Research · 2010 · 82 citations · Full text

Pathology, Neuroblastoma Correlates, Childhood Tumor Neuroblastoma +17

Activating ALK mutations found in neuroblastoma are inhibited by Crizotinib and NVP-TAE684

Christina Schönherr, Kristina Ruuth, Yasuo Yamazaki et al. · Biochemical Journal · 2011 · 80 citations · Full text

Neuro-oncology, Kinase Domain, Alk Mutations +13

Cell culture and<i>Drosophila</i>model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma

Damini Chand, Yasuo Yamazaki, Kristina Ruuth et al. · Disease Models & Mechanisms · 2012 · 60 citations · Full text