Barbara Witek

The kinase ALK stimulates the kinase ERK5 to promote the expression of the oncogene MYCN in neuroblastoma

Ganesh Umapathy, Abeer El Wakil, Barbara Witek et al. · Science Signaling · 2014 · 87 citations

Medicine, Cancer Biology, Oncology +17

The ALK inhibitor PF-06463922 is effective as a single agent in neuroblastoma driven by expression of ALK and MYCN

Jikui Guan, Elizabeth R. Tucker, Haisu Wan et al. · Disease Models & Mechanisms · 2016 · 84 citations · Full text

Medicine, Oncology, Pharmacology +17

Reprogramming of TIMP‐1 and TIMP‐3 expression profiles in brain microvascular endothelial cells and astrocytes in response to proinflammatory cytokines

Marcin Bugno, Barbara Witek, Joanna Bereta et al. · FEBS Letters · 1999 · 76 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

ALK ligand ALKAL2 potentiates MYCN‐driven neuroblastoma in the absence of ALK mutation

Marcus Borenäs, Ganesh Umapathy, Wei‐Yun Lai et al. · The EMBO Journal · 2021 · 64 citations · Full text

Medicine, Oncology, Pharmacology +17

Phosphoproteomic analysis of anaplastic lymphoma kinase (<scp>ALK</scp>) downstream signaling pathways identifies signal transducer and activator of transcription 3 as a functional target of activated <scp>ALK</scp> in neuroblastoma cells

Falko Hochgräfe, Jianmin Wu, Ganesh Umapathy et al. · FEBS Journal · 2013 · 48 citations · Full text

Life Sciences, Molecular Biology, Oncology +17