Kristina Ruuth

Anaplastic Lymphoma Kinase (ALK) regulates initiation of transcription of MYCN in neuroblastoma cells

Christina Schönherr, Kristina Ruuth, Sattu Kamaraj et al. · Oncogene · 2012 · 122 citations

Tumor Biology, Signaling Pathway, Cell Regulation +10

Antibodies to specific EBNA-1 domains and HLA DRB1⁎1501 interact as risk factors for multiple sclerosis

Peter Sundström, Maria Nyström, Kristina Ruuth et al. · Journal of Neuroimmunology · 2009 · 119 citations

Immunogenetics, Allergy, Autoimmune Disease +12

The kinase ALK stimulates the kinase ERK5 to promote the expression of the oncogene MYCN in neuroblastoma

Ganesh Umapathy, Abeer El Wakil, Barbara Witek et al. · Science Signaling · 2014 · 85 citations

The ALK inhibitor PF-06463922 is effective as a single agent in neuroblastoma driven by expression of ALK and MYCN

Jikui Guan, Elizabeth R. Tucker, Haisu Wan et al. · Disease Models & Mechanisms · 2016 · 83 citations · Full text

Appearance of the Novel Activating F1174S ALK Mutation in Neuroblastoma Correlates with Aggressive Tumor Progression and Unresponsiveness to Therapy

Tommy Martinsson, Therése Eriksson, Jonas Abrahamsson et al. · Cancer Research · 2010 · 82 citations · Full text

Pathology, Neuroblastoma Correlates, Childhood Tumor Neuroblastoma +17