Yan-Wen Mai

Design, synthesis and biological evaluation of novel 7-alkylamino substituted benzo[a]phenazin derivatives as dual topoisomerase I/II inhibitors

Bing-Lei Yao, Yan-Wen Mai, Shuo-Bin Chen et al. · European Journal of Medicinal Chemistry · 2015 · 58 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Synthesis and Mechanism Studies of 1,3-Benzoazolyl Substituted Pyrrolo[2,3-<i>b</i>]pyrazine Derivatives as Nonintercalative Topoisomerase II Catalytic Inhibitors

Penghui Li, Ping Zeng, Shuo-Bin Chen et al. · Journal of Medicinal Chemistry · 2015 · 49 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Design, synthesis and biological evaluation of novel perimidine o-quinone derivatives as non-intercalative topoisomerase II catalytic inhibitors

Du-Chao Zhou, Yuting Lu, Yan-Wen Mai et al. · Bioorganic Chemistry · 2019 · 33 citations

Pharmacy, Chemistry, Medicinal Chemistry +14

Construction of the oxaphenalene skeletons of mansonone F derivatives through C–H bond functionalization and their evaluation for anti-proliferative activities

Hua-Ting Xie, Du-Chao Zhou, Yan-Wen Mai et al. · RSC Advances · 2017 · 16 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of Quinacrine as a Potent Topo II and Hsp90 Dual-Target Inhibitor, Repurposing for Cancer Therapy

Xin Pan, Teng-yu Mao, Yan-Wen Mai et al. · Molecules · 2022 · 15 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14