Visualization of <i>NRAS</i> RNA G-Quadruplex Structures in Cells with an Engineered Fluorogenic Hybridization Probe

Shuo-Bin Chen, Minghao Hu, Guocai Liu, +5

Journal of the American Chemical Society

EngineeringNras MrnaMolecular Biological MethodMedicineRna Structure Prediction +11

Specific targeting of telomeric multimeric G-quadruplexes by a new triaryl-substituted imidazole

Ming-Hao Hu, Shuo-Bin Chen, Bo Wang, +4

Nucleic Acids Research

Combinatorial ChemistryBioorganic ChemistryMolecular BiologySiha Cancer CellsClick Chemistry +17

Discovery of a New Four-Leaf Clover-Like Ligand as a Potent <i>c-MYC</i> Transcription Inhibitor Specifically Targeting the Promoter G-Quadruplex

Ming-Hao Hu, Yuqing Wang, Ze-Yi Yu, +5

Journal of Medicinal Chemistry

Molecular BiologyC-myc PromoterCancer BiologyTumor BiologyTranscriptional Regulation +14

Development of a new colorimetric and red-emitting fluorescent dual probe for G-quadruplex nucleic acids

Jinwu Yan, Shuo-Bin Chen, Huiyun Liu, +6

Chemical Communications

Discovery of Novel Schizocommunin Derivatives as Telomeric G-Quadruplex Ligands That Trigger Telomere Dysfunction and the Deoxyribonucleic Acid (DNA) Damage Response

Tong Che, Shuo-Bin Chen, Jia-Li Tu, +10

Journal of Medicinal Chemistry

Novel Schizocommunin DerivativesMolecular BiologyDamage ResponseTumor BiologyNovel Scaffold +15

Design, synthesis, and biological evaluation of 2-arylethenylquinoline derivatives as multifunctional agents for the treatment of Alzheimer's disease

Xiaoqin Wang, Chunli Xia, Shuo-Bin Chen, +6

European Journal of Medicinal Chemistry

Medicinal ChemistryBiochemistryNatural SciencesMedicinePharmacological Agent +8

Design, synthesis and biological evaluation of novel 7-alkylamino substituted benzo[a]phenazin derivatives as dual topoisomerase I/II inhibitors

Bing-Lei Yao, Yan-Wen Mai, Shuo-Bin Chen, +9

European Journal of Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryDerivative (Chemistry)BiochemistryNatural Sciences +7

Design, synthesis and evaluation of isaindigotone derivatives as dual inhibitors for acetylcholinesterase and amyloid beta aggregation

Jinwu Yan, Yan‐Ping Li, Wen-Jie Ye, +7

Bioorganic & Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryBiochemistryDual InhibitorsNatural Sciences +8

Discovery of a new fluorescent light-up probe specific to parallel G-quadruplexes

Shuo-Bin Chen, Weibin Wu, Ming-Hao Hu, +4

Chemical Communications

Synthesis and Mechanism Studies of 1,3-Benzoazolyl Substituted Pyrrolo[2,3-<i>b</i>]pyrazine Derivatives as Nonintercalative Topoisomerase II Catalytic Inhibitors

Penghui Li, Ping Zeng, Shuo-Bin Chen, +8

Journal of Medicinal Chemistry

Medicinal ChemistryMechanism StudiesDerivativesNovel Topoisomerase IiTopo Ii Poison +13