Masao Sakairi

Discovery and pharmacological characterization of N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide hydrochloride (anagliptin hydrochloride salt) as a potent and selective DPP-IV inhibitor

Noriyasu Kato, Mitsuru Oka, Takayo Murase et al. · Bioorganic & Medicinal Chemistry · 2011 · 87 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Discovery of a potent glucokinase activator with a favorable liver and pancreas distribution pattern for the treatment of type 2 diabetes mellitus

Hiroki Fujieda, Masakazu Kogami, Masao Sakairi et al. · European Journal of Medicinal Chemistry · 2018 · 31 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Synthesis and SAR studies of bicyclic amine series GPR119 agonists

Masao Sakairi, Masakazu Kogami, Masafumi Torii et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 25 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Synthesis and pharmacological characterization of potent, selective, and orally bioavailable isoindoline class dipeptidyl peptidase IV inhibitors

Noriyasu Kato, Mitsuru Oka, Takayo Murase et al. · Organic and Medicinal Chemistry Letters · 2011 · 20 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8