Keith T. Gagnon

RNAi Factors Are Present and Active in Human Cell Nuclei

Keith T. Gagnon, Liande Li, Yongjun Chu et al. · Cell Reports · 2014 · 369 citations · Full text

Chromatin, Rnai Factors, Systems Biology +11

Allele-specific silencing of mutant huntingtin and ataxin-3 genes by targeting expanded CAG repeats in mRNAs

Jiaxin Hu, Masayuki Matsui, Keith T. Gagnon et al. · Nature Biotechnology · 2009 · 239 citations · Full text

Cag Repeats, Allele-specific Silencing, Genetics +10

Analysis of nuclear RNA interference in human cells by subcellular fractionation and Argonaute loading

Keith T. Gagnon, Liande Li, Bethany A. Janowski et al. · Nature Protocols · 2014 · 239 citations

Chromatin, Argonaute Loading, Nuclear Rna Interference +11

Promoter RNA links transcriptional regulation of inflammatory pathway genes

Masayuki Matsui, Yongjun Chu, Huiying Zhang et al. · Nucleic Acids Research · 2013 · 234 citations · Full text

Allele-Selective Inhibition of Mutant <i>Huntingtin</i> Expression with Antisense Oligonucleotides Targeting the Expanded CAG Repeat

Keith T. Gagnon, Hannah M. Pendergraff, Glen F. Deleavey et al. · Biochemistry · 2010 · 134 citations · Full text

Genetics, Molecular Biology, Therapeutics +17