Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome

Ruben A. Mars, Yi Yang, Tonya Ward, +26

Cell

Functional Gastrointestinal DisorderAutoimmune DiseaseGastroenterologyOmicsUlcerative Colitis +1

Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion

Yogesh Bhattarai, Brianna B. Williams, Eric Battaglioli, +12

Cell Host & Microbe

Increase Colonic SecretionMedicinePhysiologyGut MicrobiologyGastroenterology +7

Small intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders

George Saffouri, Robin Shields‐Cutler, Jun Chen, +21

Nature Communications

Role of gut microbiota in regulating gastrointestinal dysfunction and motor symptoms in a mouse model of Parkinson’s disease

Yogesh Bhattarai, Si Jie, Meng Pu, +9

Gut Microbes

DysbiosisHost-microbe InteractionsGastroenterologyGut MicrobiotaDigestive Tract +19

Human-derived gut microbiota modulates colonic secretion in mice by regulating 5-HT₃receptor expression via acetate production

Yogesh Bhattarai, Bradley A. Schmidt, David R. Linden, +5

American Journal of Physiology-Gastrointestinal and Liver Physiology

Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome

Ruben A. Mars, Yi Yang, Tonya Ward, +26

Cell

Functional Gastrointestinal DisorderAutoimmune DiseaseGastroenterologyOmicsUlcerative Colitis +1

Bacterially Derived Tryptamine Increases Mucus Release by Activating a Host Receptor in a Mouse Model of Inflammatory Bowel Disease

Yogesh Bhattarai, Si Jie, David R. Linden, +9

iScience

The traditional antidiarrheal remedy, Garcinia buchananii stem bark extract, inhibits propulsive motility and fast synaptic potentials in the guinea pig distal colon

Onesmo B. Balemba, Yogesh Bhattarai, Chloe Stenkamp-Strahm, +2

Neurogastroenterology & Motility

High‐fat diet–induced alterations to gut microbiota and gut‐derived lipoteichoic acid contributes to the development of enteric neuropathy

Yvonne Nyavor, Catherine R. Brands, George L. May, +12

Neurogastroenterology & Motility

High-fat diet-induced obesity alters nitric oxide-mediated neuromuscular transmission and smooth muscle excitability in the mouse distal colon

Yogesh Bhattarai, David Fried, Brian D. Gulbransen, +4

American Journal of Physiology-Gastrointestinal and Liver Physiology